主 要 学 术 成 果:
科研项目：
1、hcmv感染通过egfr介导的mapk-atf5通路影响脑胶质瘤干细胞增殖及分化的机制/国家自然科学基金
2、海藻纤维在制备新型医用止血敷料中的研发/山东省科技厅项目
3、动物源病原体的发现及其对人类致病性研究/国家自然科学基金
著作教材：
1、病原生物学与免疫学/人民卫生出版社 主编
期刊论文：
1、dna methylation level of promoter region of activating transcription factor 5 in glioma/journal of zhejiang university-science b /16(9)
2、role of treg cells and tgf-β1 in patients with systemic lupus erythematosus: a possible relation with lupus nephritis/immunol invest. 2012;41(1):15-27
3、elevated th17 cells are accompanied by foxp3 treg cells decrease in patients with lupus nephritis. rheumatol int,2012,32,949-958
4、papillary tumor of the pineal region: a case report and review of the literature/experimental and therapeutic medicine/10
5、sero-epidemiological survey of human cytomegalovirus-infected children in weifang (eastern china) between 2009 and 2012.virol [j]. 2013,10(1):42.
6、human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes. neuroreport. 2013, 24(10):526-35
7、interference with atf5 function enhances the sensitivity of human pancreatic cancer cells to paclitaxel-induced apoptosis. anticancer res. 2012 oct;32(10):4385-94
8、atf5 is overexpressed in epithelial ovarian carcinomas and interference with its function increases apoptosis through the downregulation of bcl-2 in skov-3 cells/int j gynecol pathol.2012;31(6):532-7
9、hcmv induces dysregulation of glutamate uptake and transporter expression in human fetal astrocytes. neurochem res, 2014. 39(12): 2407-18
10、upregulation of toll like receptor 2 expression in colorectal cancer infected by human cytomegalovirus/oncology letters/9: 365-370, 2015
获奖情况：
1、hcmv感染致病机制及相关的婴儿肝炎综合征/山东省科技进步奖
2、th17/treg免疫偏移在狼疮性肾炎发病中的免疫机制作用/青岛市科技进步二等奖
3、hcmv感染致病机制及相关的婴儿肝炎综合征/青岛市科学技术奖
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