一、个人简介
王瑾,青岛大学基础医学院病理系,
博士,讲师 。
二、主要研究方向
肿瘤耐药及靶向基因治疗机制
三、代表性科研成果
(1) keyu ren; chunming yong;hao yuan; bin cao; kun zhao; jin wang*, tnf-a inhibits scf, ghrelin, and substance expressions through the nf-kb pathway activation in interstitial cells of cajal. journal of medical and biological research, 2018, 51(6): e7065.
(2) jin wang ; zhantao liu; dandan zhang; ranran liu; qian lin; jia liu*; zhihongyang; qingxia ma; dantong sun; xin zhou; guohui jiang* , fl118, anovel survivin inhibitor, wins the battle against drug-resistant and meta static lung cancers through inhibition of cancer stem cell-like properties, am j transl res, 2017.8.30, 9(8): 3676-3686.
(3) jin wang ; yunqing chen; fenggang xiang; min li; hong li; keyu ren* , suppression of tgf-β1 enhances chemosensitivity of cisplatin-resistant lung cancer cells through the inhibition of drug-resistant proteins, artificial cells, nanomedicine, and biotechnology, 2018, 46(7):1505-1512.
(4) dandan zhang ; jin wang(#);zhihong yang; jia liu; zhantao liu; lixia ji; ranran liu; qian lin; guohui jiang*, a novel camptothecin analogue fl118 reduces cisplatin resistance of non-small cell lung cancer cells, int j clin exp med, 2016.6.30, 9(7): 13501-13513.
(5) jin wang ; ke-yu ren; pei-xun zhang; yan-hua wang; yu-hui kou;jian-ping peng; lei deng; hong-bo zhang; bao-guo jiang* ,effect of active notch signaling system on the early repair of rat sciatic nerve injury, artificial cells, nanomedicine and biotechnology, 2014.5, 5(28): 1-7.
四、主持的科研项目
1.中国博士后科学基金面上资助项目,喜树碱类似物fl118在p68介导下对肺癌的抑制作用研究。
2.山东省医药卫生科技发展计划,沉默tgfβ1抑制肺腺癌干细胞作用机制的探讨。
3.山东省高等学校科技计划, sirna沉默tgfβ1基因表达对肺癌顺铂耐药细胞的影响.
五、主要荣誉称号
2015年青岛大学“优秀班主任”
pg麻将胡了模拟器链接的联系方式:
e-mail:jinsmile@126.com