袁骏华,青岛大学基础医学院特种医学系,博士,助理教授,特种医学学科秘书。
一、 个人简介
2020年6月于青岛大学取得特种医学专业医学博士学位,同年8月入职青岛大学基础医学院特种医学系。参与《运动医学》、《现代特种医学》、《高压氧医学》和《特种医学前沿进展》等本科及研究生授课工作。自2017年以来,以第一/共同第一作者发表论文7篇,参与发表论文十余篇,为《medical gas research》杂志审稿专家。
二、 主要研究方向
高压氧与肥胖相关代谢疾病,脂肪因子对摄食和能量平衡的调控机制。
三、 代表性科研成果 (近五年sci论文)
1. yuan j#, jiang q#, song l, liu y, li m, lin q, li y, su k, ma z, wang y, liu d, dong j*. l-carnitine is involved in hyperbaric oxygen-mediated therapeutic effects in high fat diet-induced lipid metabolism dysfunction. molecules. 2020 jan 1;25(1):176. doi: 10.3390/molecules25010176. pmid: 31906305; pmcid: pmc6982999.
2. yuan jh#, song lm, liu y, li mw, lin q, wang r, zhang cs, dong j*. the effects of hyperbaric oxygen therapy on pelvic radiation induced gastrointestinal complications (rectal bleeding, diarrhea, and pain): a meta-analysis. front oncol. 2020 apr 9;10:390. doi: 10.3389/fonc.2020.00390. pmid: 32328454; pmcid: pmc7160697.
3. yuan jh#, chen x#, dong j*, zhang d, song k, zhang y, wu gb, hu xh, jiang zy, chen p. nesfatin-1 in the lateral parabrachial nucleus inhibits food intake, modulates excitability of glucosensing neurons, and enhances ucp1 expression in brown adipose tissue. front physiol. 2017 apr 24;8:235. doi: 10.3389/fphys.2017.00235. pmid: 28484396; pmcid: pmc5401881.
4. zhang c#, yuan j#, lin q, li m, wang l, wang r, chen x, jiang z, zhu k, chang x, wang b*, dong j*. ghrelin in the lateral parabrachial nucleus influences the excitability of glucosensing neurons, increases food intake and body weight. endocr connect. 2020 dec;9(12):1168-1177. doi: 10.1530/ec-20-0285. pmid: 33112816; pmcid: pmc7774750.
5. song l#, yuan j#, liu y, zhang d, zhang c, lin q, li m, su k, li y, gao g, ma r, dong j*. ghrelin system is involved in improvements in glucose metabolism mediated by hyperbaric oxygen treatment in a streptozotocininduced type 1 diabetes mouse model. mol med rep. 2020 nov;22(5):3767-3776. doi: 10.3892/mmr.2020.11481. epub 2020 sep 2. pmid: 32901885; pmcid: pmc7533472.
6. wang r#, yuan j#, zhang c, wang l, liu y, song l, zhong w, chen x, dong j*. neuropeptide y-positive neurons in the dorsomedial hypothalamus are involved in the anorexic effect of angptl8. front mol neurosci. 2018 dec 18;11:451. doi: 10.3389/fnmol.2018.00451. pmid: 30618603; pmcid: pmc6305345.
7. lv n#, yuan j, ji a, shi l, gao m, cui l, jiang q*. perfluorooctanoic acid-induced toxicities in chicken embryo primary cardiomyocytes: roles of ppar alpha and wnt5a/frizzled2. toxicol appl pharmacol. 2019 oct 15;381:114716. doi: 10.1016/j.taap.2019.114716. epub 2019 aug 21. pmid: 31445018.
8. liu y#, zhang d#, yuan j, song l, zhang c, lin q, li m, sheng z, ma z, lv f, gao g, dong j*. hyperbaric oxygen ameliorates insulin sensitivity by increasing glut4 expression in skeletal muscle and stimulating ucp1 in brown adipose tissue in t2dm mice. front endocrinol (lausanne). 2020 jan 31;11:32. doi: 10.3389/fendo.2020.00032. pmid: 32082261; pmcid: pmc7005601.
9. li m#, song l#, yuan j, zhang d, zhang c, liu y, lin q, wang h, su k, li y, ma z, liu d, dong j*. association between serum insulin and c-peptide levels and breast cancer: an updated systematic review and meta-analysis. front oncol. 2020 oct 29;10:553332. doi: 10.3389/fonc.2020.553332. pmid: 33194614; pmcid: pmc7658676.
10. zhang d#, yu yj, xu fs, yuan jh, wang r, zhang cs, wang lx, liu y, song lm, liu jl, dong j*. recombinant betatrophin (angptl8/lipasin) ameliorates streptozotocininduced hyperglycemia and βcell destruction in neonatal rats. mol med rep. 2019 nov;20(5):4523-4532. doi: 10.3892/mmr.2019.10719. epub 2019 oct 1. pmid: 31702044; pmcid: pmc6797976.
11. su kz#, li yr, zhang d, yuan jh, zhang cs, liu y, song lm, lin q, li mw, dong j*. relation of circulating resistin to insulin resistance in type 2 diabetes and obesity: a systematic review and meta-analysis. front physiol. 2019 nov 19;10:1399. doi: 10.3389/fphys.2019.01399. pmid: 31803062; pmcid: pmc6877503.
12. jiang q#, xu x, ni h, guo y, yuan j, zheng y*. in ovo early-in-life inhalation exposure to gas/aerosol with a chicken embryo model. methods mol biol. 2021;2326:197-201. doi: 10.1007/978-1-0716-1514-0_13. pmid: 34097269.
13. xu hc#, pang yc, chen jw, cao jy, sheng z, yuan jh, wang r, zhang cs, wang lx, dong j*. systematic review and meta-analysis of the change in ghrelin levels after roux-en-y gastric bypass. obes surg. 2019 apr;29(4):1343-1351. doi: 10.1007/s11695-018-03686-3. erratum in: obes surg. 2019 apr 10;: pmid: 30684171.
14. sheng z#, cao jy, pang yc, xu hc, chen jw, yuan jh, wang r, zhang cs, wang lx, dong j*. effects of lifestyle modification and anti-diabetic medicine on prediabetes progress: a systematic review and meta-analysis. front endocrinol (lausanne). 2019 jul 12;10:455. doi: 10.3389/fendo.2019.00455. pmid: 31354627; pmcid: pmc6639788.
15. zhang cs#, wang lx, wang r, liu y, song lm, yuan jh, wang b, dong j*. the correlation between circulating ghrelin and insulin resistance in obesity: a meta-analysis. front physiol. 2018 sep 21;9:1308. doi: 10.3389/fphys.2018.01308. pmid: 30298019; pmcid: pmc6160589.
16. fan xt#, tian z, li sz, zhai t, liu jl, wang r, zhang cs, wang lx, yuan jh, zhou y, dong j*. ghrelin receptor is required for the effect of nesfatin-1 on glucose metabolism. front endocrinol (lausanne). 2018 oct 24;9:633. doi: 10.3389/fendo.2018.00633. pmid: 30405536; pmcid: pmc6207996.
四、 主持的科研项目
国家自然科学基金青年项目,8210033261,高压氧通过nesfatin-1促进“中枢-脂肪”对话改善胰岛素抵抗的机制研究,2022/01–2024/12,24万元,在研,主持。
pg麻将胡了模拟器链接的联系方式:青岛大学浩园医学综合楼c822室,